In PoE2 each point of Strength grants +2 Maximum Life (a flat bonus, not a percentage)
Dexterity grants +5 Accuracy Rating per point and does NOT grant Evasion
Intelligence grants +2 Mana per point and does NOT grant Energy Shield
Spirit is a separate resource that pays reservations for auras, heralds and persistent minions
Travel the passive tree through Strength nodes when you need more life
Use The Hooded One to respec passives in town
Slows apply to action speed and provide a significant defensive layer
First ascendancy comes from the Act 2 Trial of the Sekhemas
Second ascendancy comes from the Trial of Chaos
Each base class has 2-3 ascendancies; there are 8 base classes and 22 ascendancies in 0.5.x
Ascendancy choices cannot be changed after selection
Blood Mage: avoid the Sanguimancy node early without proper life-cost setup
Blood Mage Sanguimancy can be refunded at The Hooded One if needed